Science is our cornerstone

We did the research so you don't have to

At OVO MD, our mission is to empower individuals with science-backed solutions that enhance immunity, reduce inflammation, and prioritize prevention, setting a new standard in proactive health and well-being. Each ingredient in our formula is responsible for specific solutions to all-to-common health obsticles.

CoQ10

Saini R. Coenzyme Q10: The essential nutrient. J Pharm Bioallied Sci. 2011 Jul;3(3):466-7. doi: 10.4103/0975-7406.84471. PMID: 21966175; PMCID: PMC3178961.
Dai S, Tian Z, Zhao D, Liang Y, Liu M, Liu Z, Hou S, Yang Y. Effects of Coenzyme Q10 Supplementation on Biomarkers of Oxidative Stress in Adults: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials. Antioxidants (Basel). 2022 Jul 13;11(7):1360. doi: 10.3390/antiox11071360. PMID: 35883851; PMCID: PMC9311997
Dludla PV, Orlando P, Silvestri S, Marcheggiani F, Cirilli I, Nyambuya TM, Mxinwa V, Mokgalaboni K, Nkambule BB, Johnson R, Mazibuko-Mbeje SE, Muller CJF, Louw J, Tiano L. Coenzyme Q10Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials. Int J Mol Sci. 2020 May 4;21(9):3247. doi: 10.3390/ijms21093247. PMID: 32375340; PMCID: PMC7247332.
Fakhrolmobasheri M, Hosseini MS, Shahrokh SG, Mohammadi Z, Kahlani MJ, Majidi SE, Zeinalian M. Coenzyme Q10 and Its Therapeutic Potencies Against COVID-19 and Other Similar Infections: A Molecular Review. Adv Pharm Bull. 2023 Mar;13(2):233-243. doi: 10.34172/apb.2023.026. Epub 2021 Nov 7. PMID: 37342382; PMCID: PMC10278218.
Fan L, Feng Y, Chen GC, Qin LQ, Fu CL, Chen LH. Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2017 May;119:128-136. doi: 10.1016/j.phrs.2017.01.032. Epub 2017 Feb 5. PMID: 28179205.
Farsi F, Heshmati J, Keshtkar A, Irandoost P, Alamdari NM, Akbari A, Janani L, Morshedzadeh N, Vafa M. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2019 Oct;148:104290. doi: 10.1016/j.phrs.2019.104290. Epub 2019 Jun 8. PMID: 31185284.
Garrido-Maraver J, Cordero MD, Oropesa-Ávila M, Fernández Vega A, de la Mata M, Delgado Pavón A, de Miguel M, Pérez Calero C, Villanueva Paz M, Cotán D, Sánchez-Alcázar JA. Coenzyme q10 therapy. Mol Syndromol. 2014 Jul;5(3-4):187-97. doi: 10.1159/000360101. PMID: 25126052; PMCID: PMC4112525
Gholami M, Zarei P, Sadeghi Sedeh B, Rafiei F, Khosrowbeygi A. Effects of coenzyme Q10 supplementation on serum values of adiponectin, leptin, 8-isoprostane and malondialdehyde in women with type 2 diabetes. Gynecol Endocrinol. 2018 Dec;34(12):1059-1063. doi: 10.1080/09513590.2018.1481944. Epub 2018 Jun 22. PMID: 29933718
Gutierrez-Mariscal FM, Arenas-de Larriva AP, Limia-Perez L, Romero-Cabrera JL, Yubero-Serrano EM, López-Miranda J. Coenzyme Q10Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases. Int J Mol Sci. 2020 Oct 23;21(21):7870. doi: 10.3390/ijms21217870. PMID: 33114148; PMCID: PMC7660335..

Zinc

Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998 Aug;68(2 Suppl):447S-463S. doi: 10.1093/ajcn/68.2.447S. PMID: 9701160.
Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatol Res Pract. 2014;2014:709152. doi: 10.1155/2014/709152. Epub 2014 Jul 10. PMID: 25120566; PMCID: PMC4120804.
Jafari F, Amani R, Tarrahi MJ. Effect of Zinc Supplementation on Physical and Psychological Symptoms, Biomarkers of Inflammation, Oxidative Stress, and Brain-Derived Neurotrophic Factor in Young Women with Premenstrual Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res. 2020 Mar;194(1):89-95. doi: 10.1007/s12011-019-01757-9. Epub 2019 Jun 2. PMID: 31154571
Afshar Ebrahimi F, Foroozanfard F, Aghadavod E, Bahmani F, Asemi Z. The Effects of Magnesium and Zinc Co-Supplementation on Biomarkers of Inflammation and Oxidative Stress, and Gene Expression Related to Inflammation in Polycystic Ovary Syndrome: a Randomized Controlled Clinical Trial. Biol Trace Elem Res. 2018 Aug;184(2):300-307. doi: 10.1007/s12011-017-1198-5. Epub 2017 Nov 10. PMID: 29127547
Mousavi SM, Djafarian K, Mojtahed A, Varkaneh HK, Shab-Bidar S. The effect of zinc supplementation on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Eur J Pharmacol. 2018 Sep 5;834:10-16. doi: 10.1016/j.ejphar.2018.07.019. Epub 2018 Jul 19. PMID: 30012497
Srnovršnik T, Virant-Klun I, Pinter B. Heavy Metals and Essential Elements in Association with Oxidative Stress in Women with Polycystic Ovary Syndrome-A Systematic Review. Antioxidants (Basel). 2023 Jul 7;12(7):1398. doi: 10.3390/antiox12071398. PMID: 37507937; PMCID: PMC10376316
Hunt JR, Beiseigel JM, Johnson LK. Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability. Am J Clin Nutr. 2008 May;87(5):1336-45. doi: 10.1093/ajcn/87.5.1336. PMID: 18469257
Peroni DG, Hufnagl K, Comberiati P, Roth-Walter F. Lack of iron, zinc, and vitamins as a contributor to the etiology of atopic diseases. Front Nutr. 2023 Jan 9;9:1032481. doi: 10.3389/fnut.2022.1032481. PMID: 36698466; PMCID: PMC9869175

Vitamin D

Vitamin D and covid-19 (2023) Natural Medicine Journal. Available at: https://www.naturalmedicinejournal.com/journal/vitamin-d-and-covid-19 (Accessed: 14 November 2023). 
The largest clinical trial to examine the effects of vitamin D supplements on the primary prevention of cancer in the general population- VITamin D and OmegA-3 TriaL (VITAL) (2023) NCT01169259
Bauer SR, Hankinson SE, Bertone-Johnson ER, Ding EL. Plasma vitamin D levels, menopause, and risk of breast cancer: dose-response meta-analysis of prospective studies. Medicine (Baltimore). 2013 May;92(3):123-131. doi: 10.1097/MD.0b013e3182943bc2. PMID: 23625163; PMCID: PMC4553988.
de Koning EJ, Lips P, Penninx BWJH, Elders PJM, Heijboer AC, den Heijer M, Bet PM, van Marwijk HWJ, van Schoor NM. Vitamin D supplementation for the prevention of depression and poor physical function in older persons: the D-Vitaal study, a randomized clinical trial. Am J Clin Nutr. 2019 Nov 1;110(5):1119-1130. doi: 10.1093/ajcn/nqz141. PMID: 31340012; PMCID: PMC6821546.
Rafiq R, Prins HJ, Boersma WG, Daniels JM, den Heijer M, Lips P, de Jongh RT. Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients: a pilot trial. Int J Chron Obstruct Pulmon Dis. 2017 Aug 28;12:2583-2592. doi: 10.2147/COPD.S132117. PMID: 28894361; PMCID: PMC5584776
Gaudet M, Plesa M, Mogas A, Jalaleddine N, Hamid Q, Al Heialy S. Recent advances in vitamin D implications in chronic respiratory diseases. Respir Res. 2022 Sep 19;23(1):252. doi: 10.1186/s12931-022-02147-x. PMID: 36117182; PMCID: PMC9483459
Xu Y, Baylink DJ, Chen CS, Reeves ME, Xiao J, Lacy C, Lau E, Cao H. The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19. J Transl Med. 2020 Aug 26;18(1):322. doi: 10.1186/s12967-020-02488-5. PMID: 32847594; PMCID: PMC7447609
Ali N. Role of vitamin D in preventing of COVID-19 infection, progression and severity. J Infect Public Health. 2020 Oct;13(10):1373-1380. doi: 10.1016/j.jiph.2020.06.021. Epub 2020 Jun 20. PMID: 32605780; PMCID: PMC7305922.
Chalmers JD, McHugh BJ, Docherty C, Govan JR, Hill AT. Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis. Thorax. 2013 Jan;68(1):39-47. doi: 10.1136/thoraxjnl-2012-202125. Epub 2012 Oct 16. PMID: 23076388
Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008 Apr;87(4):1080S-6S. doi: 10.1093/ajcn/87.4.1080S. PMID: 18400738
Meghil MM, Cutler CW. Influence of Vitamin D on Periodontal Inflammation: A Review. Pathogens. 2023 Sep 20;12(9):1180. doi: 10.3390/pathogens12091180. PMID: 37764988; PMCID: PMC10537363
Monson NR, Klair N, Patel U, Saxena A, Patel D, Ayesha IE, Nath TS. Association Between Vitamin D Deficiency and Testosterone Levels in Adult Males: A Systematic Review. Cureus. 2023 Sep 24;15(9):e45856. doi: 10.7759/cureus.45856. PMID: 37750061; PMCID: PMC10518189

Magnesium

Workinger JL, Doyle RP, Bortz J. Challenges in the Diagnosis of Magnesium Status. Nutrients. 2018 Sep 1;10(9):1202. doi: 10.3390/nu10091202. PMID: 30200431; PMCID: PMC6163803.
DiNicolantonio JJ, O'Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018 Jan 13;5(1):e000668. doi: 10.1136/openhrt-2017-000668. Erratum in: Open Heart. 2018 Apr 5;5(1):e000668corr1. PMID: 29387426; PMCID: PMC5786912.
Simental-Mendia LE, Sahebkar A, Rodriguez-Moran M, Zambrano-Galvan G, Guerrero-Romero F. Effect of Magnesium Supplementation on Plasma C-reactive Protein Concentrations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Curr Pharm Des. 2017;23(31):4678-4686. doi: 10.2174/1381612823666170525153605. PMID: 28545353
Simental-Mendía LE, Simental-Mendía M, Sahebkar A, Rodríguez-Morán M, Guerrero-Romero F. Effect of magnesium supplementation on lipid profile: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Pharmacol. 2017 May;73(5):525-536. doi: 10.1007/s00228-017-2212-8. Epub 2017 Feb 9. PMID: 28180945
Pelczyńska M, Moszak M, Bogdański P. The Role of Magnesium in the Pathogenesis of Metabolic Disorders. Nutrients. 2022 Apr 20;14(9):1714. doi: 10.3390/nu14091714. PMID: 35565682; PMCID: PMC9103223
Toprak O, Kurt H, Sarı Y, Şarkış C, Us H, Kırık A. Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study. Kidney Blood Press Res. 2017;42(1):33-42. doi: 10.1159/000468530. Epub 2017 Mar 13. PMID: 28297698
Veronese N, Watutantrige-Fernando S, Luchini C, Solmi M, Sartore G, Sergi G, Manzato E, Barbagallo M, Maggi S, Stubbs B. Effect of magnesium supplementation on glucose metabolism in people with or at risk of diabetes: a systematic review and meta-analysis of double-blind randomized controlled trials. Eur J Clin Nutr. 2016 Dec;70(12):1354-1359. doi: 10.1038/ejcn.2016.154. Epub 2016 Aug 17. Erratum in: Eur J Clin Nutr. 2016 Dec;70(12 ):1463. PMID: 27530471
Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnes Res. 2010 Dec;23(4):158-68. doi: 10.1684/mrh.2010.0220. Epub 2011 Jan 4. PMID: 21199787
Nielsen FH. Effects of magnesium depletion on inflammation in chronic disease. Curr Opin Clin Nutr Metab Care. 2014 Nov;17(6):525-30. doi: 10.1097/MCO.0000000000000093. PMID: 25023192
Balafa O, Dounousi E, Giannikouris I, Petrakis I, Georgoulidou A, Karassavidou D, Kokalis A, Stauroulopoulos A, Theodoridis M, Oikonomidis I, Triantafyllis G, Tsotsorou O, Tzannis K, Bacharaki D. Lower serum magnesium is a predictor of left ventricular hypertrophy in patients on dialysis. Int Urol Nephrol. 2023 Apr;55(4):1015-1023. doi: 10.1007/s11255-022-03391-2. Epub 2022 Oct 24. PMID: 36279086

Curcumin

Panknin TM, Howe CL, Hauer M, Bucchireddigari B, Rossi AM, Funk JL. Curcumin Supplementation and Human Disease: A Scoping Review of Clinical Trials. Int J Mol Sci. 2023 Feb 24;24(5):4476. doi: 10.3390/ijms24054476. PMID: 36901908; PMCID: PMC10003109
Howells L, Malhotra Mukhtyar R, Theofanous D, Pepper C, Thomas A, Brown K, Khan S. A Systematic Review Assessing Clinical Utility of Curcumin with a Focus on Cancer Prevention. Mol Nutr Food Res. 2021 Jul;65(13):e2000977. doi: 10.1002/mnfr.202000977. Epub 2021 Jun 3. PMID: 34015183
Satoskar RR, Shah SJ, Shenoy SG. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166
Roy M, Sinha D, Mukherjee S, Biswas J. Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic-exposed human population in West Bengal, India. Eur J Cancer Prev. 2011 Mar;20(2):123-31. doi: 10.1097/cej.0b013e328341017a. PMID: 21332098
Heshmati J, Golab F, Morvaridzadeh M, Potter E, Akbari-Fakhrabadi M, Farsi F, Tanbakooei S, Shidfar F. The effects of curcumin supplementation on oxidative stress, Sirtuin-1 and peroxisome proliferator activated receptor γ coactivator 1α gene expression in polycystic ovarian syndrome (PCOS) patients: A randomized placebo-controlled clinical trial. Diabetes Metab Syndr. 2020 Mar-Apr;14(2):77-82. doi: 10.1016/j.dsx.2020.01.002. Epub 2020 Jan 8. PMID: 31991296
Fadinie, W., A. Lelo, D. W. Wijaya, And S. N. Lumbanraja. “Curcumin And Its Effect On Preeclampsia: As Anti-Inflammatory, Analgesic, And Anticoagulant”.International Journal Of Current Pharmaceutical Research, Vol. 12, No. 2, Mar. 2020, Pp. 43-47, Doi:10.22159/Ijcpr.2020V12I2.37485
Samadian F, Dalili N, Poor-Reza Gholi F, Fattah M, Malih N, Nafar M, Firoozan A, Ahmadpoor P, Samavat S, Ziaie S. Evaluation of Curcumin's effect on inflammation in hemodialysis patients. Clin Nutr ESPEN. 2017 Dec;22:19-23. doi: 10.1016/j.clnesp.2017.09.006. Epub 2017 Oct 5. PMID: 29415829.
Khajehdehi P, Zanjaninejad B, Aflaki E, Nazarinia M, Azad F, Malekmakan L, Dehghanzadeh GR. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr. 2012 Jan;22(1):50-7. doi: 10.1053/j.jrn.2011.03.002. Epub 2011 Jul 13. PMID: 21742514.
Kalluru H, Kondaveeti SS, Telapolu S, Kalachaveedu M. Turmeric supplementation improves the quality of life and hematological parameters in breast cancer patients on paclitaxel chemotherapy: A case series. Complement Ther Clin Pract. 2020 Nov;41:101247. doi: 10.1016/j.ctcp.2020.101247. Epub 2020 Oct 13. PMID: 33099272.
Nouri-Vaskeh M, Malek Mahdavi A, Afshan H, Alizadeh L, Zarei M. Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: A randomized controlled trial. Phytother Res. 2020 Jun;34(6):1446-1454. doi: 10.1002/ptr.6620. Epub 2020 Feb 3. PMID: 32017253.

Hemp Seed

Farinon B, Molinari R, Costantini L, Merendino N. The seed of industrial hemp (Cannabis sativaL.): Nutritional Quality and Potential Functionality for Human Health and Nutrition. Nutrients. 2020 Jun 29;12(7):1935. doi: 10.3390/nu12071935. PMID: 32610691; PMCID: PMC7400098
Polaczek K, Kurańska M. Hemp Seed Oil and Oilseed Radish Oil as New Sources of Raw Materials for the Synthesis of Bio-Polyols for Open-Cell Polyurethane Foams. Materials (Basel). 2022 Dec 13;15(24):8891. doi: 10.3390/ma15248891. PMID: 36556696; PMCID: PMC9785633..
Amiri-Rigi A, Kesavan Pillai S, Naushad Emmambux M. Development of hemp seed oil nanoemulsions loaded with ascorbyl palmitate: Effect of operational parameters, emulsifiers, and wall materials. Food Chem. 2023 Jan 30;400:134052. doi: 10.1016/j.foodchem.2022.134052. Epub 2022 Sep 1. PMID: 36067691
Lopez C, Novales B, Rabesona H, Weber M, Chardot T, Anton M. Deciphering the properties of hemp seed oil bodies for food applications: Lipid composition, microstructure, surface properties and physical stability. Food Res Int. 2021 Dec;150(Pt A):110759. doi: 10.1016/j.foodres.2021.110759. Epub 2021 Oct 17. PMID: 34865777.
Vitorović J, Joković N, Radulović N, Mihajilov-Krstev T, Cvetković VJ, Jovanović N, Mitrović T, Aleksić A, Stanković N, Bernstein N. Antioxidant Activity of Hemp (Cannabis sativaL.) Seed Oil inDrosophila melanogasterLarvae under Non-Stress and H2O2-Induced Oxidative Stress Conditions. Antioxidants (Basel). 2021 May 22;10(6):830. doi: 10.3390/antiox10060830. PMID: 34067432; PMCID: PMC8224776
Farì G, Megna M, Scacco S, Ranieri M, Raele MV, Chiaia Noya E, Macchiarola D, Bianchi FP, Carati D, Panico S, Di Campi E, Gnoni A, Scacco V, Inchingolo AD, Qorri E, Scarano A, Rapone B. Hemp Seed Oil in Association with β-Caryophyllene, Myrcene and Ginger Extract as a Nutraceutical Integration in Knee Osteoarthritis: A Double-Blind Prospective Case-Control Study. Medicina (Kaunas). 2023 Jan 18;59(2):191. doi: 10.3390/medicina59020191. PMID: 36837393; PMCID: PMC9960141..

Garlic

Ansary J, Forbes-Hernández TY, Gil E, Cianciosi D, Zhang J, Elexpuru-Zabaleta M, Simal-Gandara J, Giampieri F, Battino M. Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview. Antioxidants (Basel). 2020 Jul 15;9(7):619. doi: 10.3390/antiox9070619. PMID: 32679751; PMCID: PMC7402177.
Petropoulos S., Fernandes Â., Barros L., Ciric A., Sokovic M., Ferreira I.C. Antimicrobial and antioxidant properties of various Greek garlic genotypes.Food Chem.2018;245:7–12. doi: 10.1016/j.foodchem.2017.10.078.
Szulińska M., Kręgielska-Narożna M., Świątek J., Styś P., Kuźnar-Kamińska B., Jakubowski H., Walkowiak J., Bogdański P. Garlic extract favorably modifies markers of endothelial function in obese patients–randomized double blind placebo-controlled nutritional intervention.Biomed. Pharmacother.2018;102:792–797. doi: 10.1016/j.biopha.2018.03.131.
Serrano A., Ros G., Nieto G. Bioactive compounds and extracts from traditional herbs and their potential anti-inflammatory health effects.Medicines.2018;5:76. doi: 10.3390/medicines5030076.
Xu C., Mathews A.E., Rodrigues C., Eudy B.J., Rowe C.A., O’Donoughue A., Percival S.S. Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.Clin. Nutr. ESPEN.2018;24:148–155. doi: 10.1016/j.clnesp.2017.11.010.
Ishikawa H., Saeki T., Otani T., Suzuki T., Shimozuma K., Nishino H., Fukuda S., Morimoto K. Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.J. Nutr.2006;136:816S–820S. doi: 10.1093/jn/136.3.816S.
Atkin M., Laight D., Cummings M.H. The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial.J. Diabetes Complicat.2016;30:723–727. doi: 10.1016/j.jdiacomp.2016.01.003.

Vitamin C

Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr. 1999 Jun;69(6):1086-107. doi: 10.1093/ajcn/69.6.1086. PMID: 10357726.
Shekelle P, Morton S, Hardy ML. Effect of supplemental antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cardiovascular disease. Evid Rep Technol Assess (Summ). 2003 Jun;(83):1-3. PMID: 15040141; PMCID: PMC4781262
Shekelle P, Hardy ML, Coulter I, Udani J, Spar M, Oda K, Jungvig LK, Tu W, Suttorp MJ, Valentine D, Ramirez L, Shanman R, Newberry SJ. Effect of the supplemental use of antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cancer. Evid Rep Technol Assess (Summ). 2003 Oct;(75):1-3. PMID: 15523748; PMCID: PMC4781200.
Son YS, Ullah HMA, Elfadl AK, Chung MJ, Ghim SG, Kim YD, Lee EJ, Kang KK, Jeong KS. Preventive Effects of Vitamin C on Diethylnitrosamine-induced Hepatotoxicity inSmp30Knockout Mice. In Vivo. 2018 Jan-Feb;32(1):93-99. doi: 10.21873/invivo.11209. PMID: 29275304; PMCID: PMC5892647.
van Leeuwen R, Boekhoorn S, Vingerling JR, Witteman JC, Klaver CC, Hofman A, de Jong PT. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA. 2005 Dec 28;294(24):3101-7. doi: 10.1001/jama.294.24.3101. PMID: 16380590.
Levine M, Wang Y, Padayatty SJ, Morrow J. A new recommended dietary allowance of vitamin C for healthy young women. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9842-6. doi: 10.1073/pnas.171318198. PMID: 11504949; PMCID: PMC55540
.Sesso HD, Buring JE, Christen WG, Kurth T, Belanger C, MacFadyen J, Bubes V, Manson JE, Glynn RJ, Gaziano JM. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA. 2008 Nov 12;300(18):2123-33. doi: 10.1001/jama.2008.600. Epub 2008 Nov 9. PMID: 18997197; PMCID: PMC2586922.
Al-Khudairy L, Flowers N, Wheelhouse R, Ghannam O, Hartley L, Stranges S, Rees K. Vitamin C supplementation for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2017 Mar 16;3(3):CD011114. doi: 10.1002/14651858.CD011114.pub2. PMID: 28301692; PMCID: PMC6464316.
Lin J, Cook NR, Albert C, Zaharris E, Gaziano JM, Van Denburgh M, Buring JE, Manson JE. Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. J Natl Cancer Inst. 2009 Jan 7;101(1):14-23. doi: 10.1093/jnci/djn438. Epub 2008 Dec 30. PMID: 19116389; PMCID: PMC2615459.

Ginger

Bode AM, Dong Z. The Amazing and Mighty Ginger. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 7.Available from: https://www.ncbi.nlm.nih.gov/books/NBK92775/
Chrubasik S, Pittler MH, Roufogalis BD. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine. 2005 Sep;12(9):684-701. doi: 10.1016/j.phymed.2004.07.009. PMID: 16194058.
Baloghová J, Michalková R, Baranová Z, Mojžišová G, Fedáková Z, Mojžiš J. Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy. Molecules. 2023 Aug 25;28(17):6251. doi: 10.3390/molecules28176251. PMID: 37687080; PMCID: PMC10489044.
Bi X, Lim J, Henry CJ. Spices in the management of diabetes mellitus. Food Chem. 2017 Feb 15;217:281-293. doi: 10.1016/j.foodchem.2016.08.111. Epub 2016 Aug 29. PMID: 27664636.
Dedov VN, Tran VH, Duke CC, Connor M, Christie MJ, Mandadi S, Roufogalis BD. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br J Pharmacol. 2002 Nov;137(6):793-8. doi: 10.1038/sj.bjp.0704925. PMID: 12411409; PMCID: PMC1573550.
El-Sharaky AS, Newairy AA, Kamel MA, Eweda SM. Protective effect of ginger extract against bromobenzene-induced hepatotoxicity in male rats. Food Chem Toxicol. 2009 Jul;47(7):1584-90. doi: 10.1016/j.fct.2009.04.005. Epub 2009 Apr 23. PMID: 19371770.
Alsherbiny MA, Abd-Elsalam WH, El Badawy SA, Taher E, Fares M, Torres A, Chang D, Li CG. Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review. Food Chem Toxicol. 2019 Jan;123:72-97. doi: 10.1016/j.fct.2018.10.048. Epub 2018 Oct 22. PMID: 30352300.
Yahyazadeh R, Baradaran Rahimi V, Yahyazadeh A, Mohajeri SA, Askari VR. Promising effects of gingerol against toxins: A review article. Biofactors. 2021 Nov;47(6):885-913. doi: 10.1002/biof.1779. Epub 2021 Aug 21. PMID: 34418196.
de Lima RMT, Dos Reis AC, de Menezes APM, Santos JVO, Filho JWGO, Ferreira JRO, de Alencar MVOB, da Mata AMOF, Khan IN, Islam A, Uddin SJ, Ali ES, Islam MT, Tripathi S, Mishra SK, Mubarak MS, Melo-Cavalcante AAC. Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]-gingerol in cancer: A comprehensive review. Phytother Res. 2018 Oct;32(10):1885-1907. doi: 10.1002/ptr.6134. Epub 2018 Jul 16. PMID: 30009484.
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